Acetylcholine, choline

[Flavio]

Nitric oxide (NO) is the most important neurotransmitter involved in penile erections, but experts seem to agree that the chemical neurotransmitter acetylcholine is also important and helps facilitate erections. Future ED treatments may use this pathway to improve male sexual health.

According to Dr Tom Lue (in 'Physiology of Penile Erection'):

«It has been suggested that acetylcholine stimulates the release of NO from endothelial cells and thus contributes directly to smooth muscle relaxation during erection.»

A more recent study states that:

«There is no doubt that the release of neurotransmitters from the sympathetic, parasympathetic, dopaminergic and serotonergic nervous systems, e.g. adrenaline, noradrenaline, acetylcholine, dopamine and serotonin, mainly contribute to the regulation of penile smooth muscle tone.»

As far as I know, there are no acetylcholine supplements but a choline supplement, a precursor to acetylcholine, may be useful.

[brar]

Is acetylcholine an active ingredient in any Erectile Dysfunction medication on the market? Is it similar to PDE-5? Read allot about it here Acetylcholine - Wikipedia, the free encyclopedia but it is allot of medical mambo jambo that I do not understand..

[Flavio]

Is acetylcholine an active ingredient in any Erectile Dysfunction medication on the market? Is it similar to PDE-5? Read allot about it here Acetylcholine - Wikipedia, the free encyclopedia but it is allot of medical mambo jambo that I do not understand..

I'm not an expert but I know there are drugs and supplements that can improve acetylcholine levels. If anyone has more info on this, please keep us posted.